CDK6 Antikörper

Produktnummer ABIN488121

Dieses Anti-CDK6-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CDK6 in WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CDK6 Antikörper (ABIN488121)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: DCS-83

Produktdetails anti-CDK6 Antikörper

Spezifität: This antibody reacts with Cdk6.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Protein-A Sepharose Chromatography.

Immunogen: Recombinant Cdk6 protein. Remarks: Hybridoma was established by fusion of mouse myeloma cell NS-2 with Balb/c mouse splenocyte.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 50 % Glycerol without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Andere Bezeichnung: CDK6

Hintergrund: Cdk6 (Cyclin-dependent kinase-6) is a 38-40 kDa member of the Cdk family of mitotic kinases involved in cell cycle progression. The Cdk6 phosphoprotein, like Cdk4, associates with D-cyclins to regulate cell proliferation. Following translocation to the nucleus, the Cdk6 is phosphorylated by CAK, and the Cdk6 complex, in association with PCNA, phosphorylates the retinoblastoma (Rb) protein. Overexpression of Cdk6 has been associated with several different types of cancer.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE

Gen-ID: 1021

NCBI Accession: NP_001250

UniProt: Q00534

Pathways: Zellzyklus, Mitotic G1-G1/S Phases